Several factors contribute to cause bipolar disorder and its precise mechanism escapes us. However, there is strong evidence that biological factors - including genetic - play an important role .
This does not mean that a person must inherit genes : genes in question may be modified at the time of conception.
Genes regulate the formation of cells and their contents . The scientists believe that genetic changes can cause the production of defective proteins in brain cells . These proteins can then cause bipolar disorder. Today , researchers are studying different proteins that may be involved in this disease :
the proteins involved in the production of chemicals called neurotransmitters in the brain ;
proteins that use neurotransmitters to give orders to the cells ;
the genes themselves .
What is sure, is that too much stress or family problems can not cause the disease , but can "trigger" an episode in people who already have .
Bipolar disorder is not a simple imbalance of neurotransmitters such as serotonin and dopamine. However, an outbreak of the disease can affect these neurotransmitters.
What can trigger a bipolar episode ?
If all the episodes can be attributed to a trigger factor , however many can be. Triggers are situations that can cause mania or depression in a person who has been through a bipolar episode. An intense period of stress or insomnia are examples .
Some triggers are chemical and include antidepressants that work "too well" and cause mania , current medications, such as steroids (eg , prednisone used in the treatment of asthma or arthritis ) , and illicit drugs such as cocaine and amphetamines.
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